Successful weight loss requires a life long change in eating and activity behaviors....quick fixes, such as diet pills and diet and exercise programs only work in the short-term.
"Dr. Caroline Apovian, director of the center for nutrition and weight management at Boston University Medical Center, who has consulted for drug companies, said, “We’ve shown over and over again that it’s very difficult for anyone to lose weight and keep it off through diet and exercise alone.” When that approach is successful, she said, it often requires intensive coaching, which is impractical for medical offices to provide on a large scale. "
http://www.nytimes.com/2010/10/29/health/policy/29drug.html?_r=1&emc=na